Sucrose is sugar. Sucralose (Splenda) is chlorinated sugar; a chlorocarbon.
The term 'Chlorocarbon' is used for any chemical compound that contains both atoms of Carbon, and Chlorine. Cholocarbons are typically poisons.
Sucralose is a molecule of sugar which is chemically manipulated to surrender three hydroxyl groups (hydrogen + oxygen) and replace them with three chlorine atoms.
Recall what Jorge says about Chlorine to better understand the problems associated with Sucralose.
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